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September 5, 2008
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Transgenics anonymous. by Velica Transgenics anonymous. by Velica
Mice are still the best model for mammal genetics and physiology. Small, docile and cheap these little fellas are one of the main reasons why science (specially medical science) keeps advancing so quickly.

Nowadays many labs can generate mice lacking certain genes of interest by simple manipulation of mouse embryonic stem cells. There is a huge array of "mutated" mice strains about.

I thought it would be funny if they got together and discussed their griefs.

(p53 is a very important gene, involved in the development of cancer)
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:iconmrspanyard:
MrSpanyard Featured By Owner Jun 2, 2014
Point mutation on p53, aka, genome guardian, doesn't have to lead to cancer right away. It can only be a silent mutartion, or a revertant one. Or maybe the mouse just dies before the mutation can actually cause any vissible effect.
Maybe the joke was "what if" maybe?
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:iconph0xy:
Ph0Xy Featured By Owner Jun 2, 2012  Hobbyist Photographer
Don't you mean, anonyMOUSE? I'll leave now, sorry. ):
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:iconvelica:
Velica Featured By Owner Jun 3, 2012
hahaha
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:iconemmetearwax:
EmmetEarwax Featured By Owner Oct 21, 2010  Hobbyist Writer
Isn't P53 the self-destruct trigger in a cell, supposed to activate if a cell has gone mutant ,detected by a white-blood immune cell and receives the "commence P53 self-destruct" command from it ?

P53 initiated self-destruct is involved in embryonic development to destroy tissues and even organs that have served their purpose (such as separating the fingers from each other, and even forming the hole that becomes the mouth, not to mention the first pair of kidneys and much of the 2nd pair, leaving us with the third pair.)
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:iconvelica:
Velica Featured By Owner Oct 21, 2010
Thank you Mr Wikipedia.
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:iconspikeghost:
Spikeghost Featured By Owner May 19, 2010
aww :( poor lil things :(
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:iconpicklenation:
picklenation Featured By Owner Feb 16, 2010  Student Artist
HAHAHAHAHA. THIS IS SO CLEVER!
I love it!
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:iconmentalrabie:
Mentalrabie Featured By Owner Sep 11, 2008
heheh
i hope, you'll make more bio-geeky cartoons, they're funny *and* informative...
btw: is the freaks of science-series closed? :(
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:iconvelica:
Velica Featured By Owner Sep 12, 2008
:) thanks.

Well, technically no series is ever closed but I tend to drift away from them. I've been feeling quite uninspired recently...
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:iconmentalrabie:
Mentalrabie Featured By Owner Sep 12, 2008
that's too bad. i *loved* your freaks of science! :nod:
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