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March 20, 2008
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Freaks of Science: P. Pezzino by Velica Freaks of Science: P. Pezzino by Velica
::This deviation is part of the colection FREAKS OF SCIENCE. [link] ::

Favourite colour:
misty rose

Medical file:
After many years of research in the ubiquitination area, Prof Pezzino began to develop an agravated paranoia syndrome. He claimed he had been targeted for degradation and has been living a life of fear since then. He is ofter troubled with nightmares where he is chased by a demonic proteasome threating to kill him. Prof Pezzino showers three times per day to “wash away the ubiquitin residues”.

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Note:
Inside the cells proteins are produced and degraded according needs. When proteins need to be quickly degraded they get ubiquitinated, i.e., a series of ubiquitine groups are added to the target protein, marking it to degradation. [link]
I often look at this mechanism as a small Mafia inside each cell. This is the whole basis of Dr Pezzinos joke. Of course he had to be Italian.
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:iconthepathofdreams:
HAHAHA!!! This made me laugh out loud!
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:iconcool-slayer:
cool-slayer Apr 1, 2008  Hobbyist Digital Artist
adoro esta série de desenhos, misturas a ciência com o humor e é uma mistura que resulta num desenho e numa ideia muito porreiras ;) continua!
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:iconmentalrabie:
this series rocks! :)
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:iconthe-mirrorball-man:
The-Mirrorball-Man Mar 22, 2008  Hobbyist Digital Artist
This one must be my favorite in the series (so far).
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:icondunwich7:
Another winner :)

(well, ok, he's more like a looser, but you know what I mean)

I think I will insert "ubiquitination" into my vocabulary.
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:iconvelica:
it may save your life!
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:iconlexmontypython:
«;Prof Pezzino showers three times per day to “wash away the ubiquitin residues”.»

Fixe, isso faz-me lembrar a paranóia do Howard Hughes com a higiene!
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